منابع مشابه
Mac OS 9 - the missing manual
This is the second edition of the Honeynet Project’s opus, and I was interested in seeing what had been added. If you follow the Honeynet Project closely, a lot will be familiar. But the second half of the book contains forensics case studies that will alone be worth the purchase price for many readers. Well, there is a root account in MacOS X; you just need to know how to enable it. The Missin...
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The tight coupling of protein folding pathways with disposal mechanisms promotes the efficacy of protein production in the endoplasmic reticulum (ER). It has been hypothesized that the ER-resident molecular chaperone glucose-regulated protein 94 (GRP94) is part of this quality control coupling because it supports folding of select client proteins yet also robustly associates with the lectin ost...
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The basic virtual memory-mapped communication (VMMC) model provides protected, direct communication between the sender's and receiver's virtual address spaces, but it does not support high-level connection-oriented communication APIs well. This paper presents VMMC-2, an extension to the basic VMMC. We describe the design, implementation , and evaluate the performance of three mechanisms in VMMC...
متن کاملStringent requirement for HRD1, SEL1L, and OS-9/XTP3-B for disposal of ERAD-LS substrates
Sophisticated quality control mechanisms prolong retention of protein-folding intermediates in the endoplasmic reticulum (ER) until maturation while sorting out terminally misfolded polypeptides for ER-associated degradation (ERAD). The presence of structural lesions in the luminal, transmembrane, or cytosolic domains determines the classification of misfolded polypeptides as ERAD-L, -M, or -C ...
متن کاملHypoxia Associated Proteolytic Processing of OS-9 by the Metalloproteinase Meprin β
Meprin metalloproteases play a role in the pathology of ischemia/reperfusion- (IR-) induced renal injury. The endoplasmic reticulum-associated protein, osteosarcoma-9 (OS-9), has been shown to interact with the carboxyl-terminal tail of meprin β. More importantly, OS-9 interacts with the hypoxia inducible factor-1α (HIF-1α) and the prolyl-hydroxylase, proteins which mediate the cell's response ...
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ژورنال
عنوان ژورنال: Molecular Cell
سال: 2005
ISSN: 1097-2765
DOI: 10.1016/j.molcel.2005.02.001